For couples whose infertility persists despite conventional first-line treatments, in vitro fertilization (IVF) offers a logical next step.
With pregnancy rates up to five times that of intrauterine insemination, IVF is the most effective fertility treatment available today. It is the most common form of fertility treatment and is particularly helpful for women of advanced age, women with damaged fallopian tubes, female with endometriosis , male factor infertility, and unexplained infertility.
OUR IVF SUCCESS
Here at the Renji International VIP Department, we specialize in IVF. Renji Hospital has built a reputation as a respected source for this advanced reproductive technology and as a Tier 3A Hospital is proud to utilize the most advanced technology and equipment in the world. We offer a variety of modifications to the standard IVF process to help patients with specific disorders.
Our dedicated Reproductive Medical Center and IVF experts lead by our international director, Dr. Steven Lindheim, offer the experience, technologies, guidance, and support to help you achieve an IVF pregnancy in the shortest time possible.
Our ability to treat both routine and complicated cases is a testament to the Renji team that includes more than a 100 physicians, nurses, scientists, PhDs, embryologists, and lab technicians who together provide you with valuable insight, unique perspectives, and world-class care that maximizes your success.
• During IVF, eggs are collected from a woman's ovaries through the vagina in an outpatient surgical procedure and fertilized by sperm in our lab
• If the male partner has an abnormal sperm, then fertilization can be achieved by injecting a single sperm into each egg in a process called Intra-Cytoplasmic Sperm Injection (ICSI)
• In the process of assisted reproduction,individualized ovarian stimulation program and medicine contronalled ovulation will be performed,inorder to obtain more eggs.This process takes about 2-4 weeks, culminating in multiple eggs being retrieved from a woman's ovaries and fertilized with sperm
• The fertilized eggs, now called embryos, are then implanted into the woman's uterus three to five days after fertilization - or may be frozen for use. Embryo transfer could be performed after rest and relaxation.
• The Ruiwen IVF team will work with you to determine an individualized and appropriate pathway to help you achieve your goals in creating or growing your family
IVF provides many people with the opportunity to attempt pregnancy in the face of one or more factors that may otherwise decrease their chances. Below you will find the most common reasons for women/couples to consider IVF treatment.
REASONS TO CHOOSE IVF
• Those who have been unsuccessful with simpler treatments including IUI
• Age-related infertility
• Low ovarian reserve
• Recurrent miscarriage
• Those who carry or have a family history of genetic defects
• Women with blocked or damaged fallopian tubes
• Unable to ovulate including polycystic ovary syndrome (PCOS)
• Men with poor sperm quality or quantity
• Unexplained infertility
At the Renji International VIP Department, the IVF process is characterized by a variety of different stages. They include:
Your initial consultation, the very first step in the IVF process, is an opportunity for your Ruiwen IVF clinical team to learn more about your medical history and begin to design a customized IVF treatment plan that addresses your goals and maximizes your success. Once a comprehensive work-up that includes blood work to assess ovarian reserve, pelvic ultrasound, and a semen analysis have been completed, your care team will prepare you to begin your IVF cycle.
CONTROLLED OVARIAN HYPERSTIMULATION
Normally, a woman produces one egg per month in her menstruation cycle. Ovulation induction medications send signal to the ovaries to promote the development of multiple follicles. This process of stimulation may continue for eight to twelve days, in the meantime, your nursing team will monitor the ovarian status by ultrasound and monitor the hormone levels through blood tests to monitor the ovulation induction process. Once the follicles are mature in size, egg maturation is further induced by injection of HCG (human chorionic gonadotropin) and/or GnRHa (gonadotropin releasing hormone agonist).
Approximately, thirty-six hours after the HCG／GnRHa injection, the eggs are removed from the woman's ovaries. To collect mature eggs from the woman's body, a physician at the Renji International VIP department performs a minor outpatient surgery under the guidance of transvaginal ultrasound, retrieving eggs through vaginal puncture. The surgery is a short 10 to 15-minute procedure performed at the state of art, Renji Reproductive Medical Center. An intravenous anesthesia is administered to ensure comfort. Most women are able to return home within an hour after the procedure. On the same day, your partner will provide a fresh semen sample to our lab. If you have obtained frozen donor sperm, we will ensure this sample has been received and tested prior to your retrieval. Following egg retrieval, you will begin progesterone to prepare for the embryos being transferred back to the uterus. Implantation typically will occur three to five days later.
Our embryologists combine the eggs with sperm for fertilization within a few hours after insemination. Fertilized eggs, now called embryos, are kept in our incubators to develop further. If your embryologist thinks the chance of fertilization is low, the sperm may be directly injected into the egg. This process is called ICSI.
Our team of embryologists will regularly monitor your embryos to assure they are growing properly. Within five to six days, a normal embryo develops into many cells (>150) that are actively dividing. At this point, couples with a risk of passing on a genetic disorder to their child may consider undergoing preimplantation genetic testing (PGT). Renji utilizes the most advanced genetic testing in China. Our embryologists will assess embryo quality according to internationally harmonized standards. We will select embryos with best quality to increase your chances of successful and healthy conception.
Three to five days after egg retrieval and fertilization, embryos are typically transferred into the woman's uterus. This procedure (similar to a Pap smear) occurs in the Renji procedure room using a catheter inserted through the cervix that takes less then few minutes to perform. Most women are able to resume regular activities the next day. If an embryo implants to the uterine lining and grows, pregnancy results. Any unused high quality embryos may be frozen to allow the option of future implantation.
To help assure the uterine lining is most receptive for the embryo to implant, you will continue progesterone therapy for two weeks after embryo transfer. A blood test for pregnancy is performed fourteen days after the embryo transfer. If pregnancy is confirmed, you will continue progesterone until your placenta produces enough hormones to support the pregnancy on its own. If a pregnancy cannot be confirmed, you may decide with your doctor to begin another cycle of IVF.